Education | Laboratory Personnel | General Research Interest
Selected Publications
TCSVM Faculty

Jean M. Mukherjee
Assistant Professor
Department of Biomedical Sciences
Division of Infectious Diseases
Phone: 508-887-4756
Email: jean.mukherjee@tufts.edu
Dept. URL:http://www.tufts.edu/vet/dbs/infectious_diseases/

Education

DACVM - Diplomate American College of Veterinary Medicine - 2011
DVM - University of Minnesota College of Veterinary Medicine - 1996
PhD - Albert Einstein College of Medicine - 1992
MS - Albert Einstein College of Medicine - 1991
BA - Hamline University - 1989

Board Certification

Diplomate of the American College of Veterinary Microbiologists (DACVM)


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Laboratory Personnel

Karen Baldwin, Animal Specialist
Courtney Boucher, Research Technician
Kwasi Ofori, Research Assistant

General Research Interest

Development of immune-based methods for diagnosis, therapy, and prevention of infectious and toxin-mediated diseases of human, veterinary and/or zoonotic concern; animal model development; in vivo evaluation of candidate therapeutics; veterinary microbiology and parasitology.

Research and Clinical Interests

  • Passive Immunotherapy
  • Microbial Pathogenesis
  • Conjugate Vaccines

 

 

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Selected Publications

  1. Mukherjee, J., J.M. Tremblay, C.E. Leysath, K. Ofori, K. Baldwin, X. Feng, D. Bedenice, S. Tzipori, and C.B. Shoemaker.  2011.  A Novel Strategy for Development or Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model.”  Plos One 7:1-7e29941.

  2. Sepulveda, J., J. Mukherjee, S. Tzipori, L. Simpson, C. Shoemaker.  2010.  “Efficient serum clearance of botulinum neurotoxin using a pool of small antitoxin binding agents."  Infection and Immunity  78(2):756-763.

  3. Mukherjee, J., K. Chios, D. Fishwild, D. Hudson, S. O’Donnell, S. Rich, A. Donohue-Rolfe, and S. Tzipori.  2002.  “Production and Characterization of Protective Human Antibodies Against Shiga-Toxin 1 (Stx1).”  Infection and Immunity 70(10):5896-5899.

  4. Mukherjee, J., K. Chios, D. Fishwild, D. Hudson, S. O’Donnell, S. Rich, A. Donohue-Rolfe, and S. Tzipori.  2002.  “Human Stx2 Antibodies Prevent Systemic Complications of Escherichia coli 0157:H7 Infection.”  Infection and Immunity  70(2):612-619.

  5. Mukherjee, J., M.D. Scharff, and A. Casadevall.  1995.  "Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Enhance Fluconazole Efficacy."  Antimicrobial Agents and Chemotherapy  39:1398-1405.

  6. Mukherjee, J., M.D. Scharff, and A. Casadevall.  1995.  "Variable Efficacy of Passive Antibody Administration Against Diverse Cryptococcus neoformans Strains."  Infection and Immunity  63:3353-3359.

  7. Mukherjee, J., G. Nussbaum, M.D. Scharff, and A. Casadevall.  1995.  "Somatic Mutation Can Generate Differences in Specificity that Change the Protective Efficacy of Antibodies to Cryptococcus neoformans."  Journal of Experimental Medicine  181:405-409.

  8. Mukherjee, J., L.S. Zuckier, M.D. Scharff, and A. Casadevall.  1994.  "Therapeutic Efficacy of Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Alone and in Combination with Amphotericin B."  Antimicrobial Agents and Chemotherapy  38:580-587.

  9. Mukherjee, J., L.-A. Pirofski, M.D. Scharff, and A. Casadevall.  1993.  "Antibody-Mediated Protection in Mice with Lethal Intracerebral Cryptococcus neoformans Infection."  Proceedings of the National Academy of Science (PNAS)  90:3636-3640.

  10. Mukherjee, J., A. Casadevall, and M.D. Scharff.  1993.  "Molecular Characterization of the Humoral  Responses to Cryptococcus neoformans Infection and Glucuronoxylomannan-Tetanus Toxoid Conjugate  Immunization."  Journal of Experimental Medicine  177:1105-1116.

 

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