Education | Laboratory Personnel | General Research Interest
Selected Publications
TCSVM Faculty

Jean Mukherjee
Assistant Professor
Department of Infectious Disease and Global Health
Phone: 508-887-4756
Email:Jean.Mukherjee@tufts.edu
Dept. URL:http://www.tufts.edu/vet/dbs/infectious_diseases/

Education

DVM - University of Minnesota College of Veterinary Medicine - 1996
PhD - Albert Einstein College of Medicine - 1992
MS - Albert Einstein College of Medicine - 1991
BA - Hamline University - 1989

Board Certification

Diplomate of the American College of Veterinary Microbiologists (DACVM)


Back to the Top

Laboratory Personnel

Karen Baldwin, Animal Specialist
Courtney Boucher, Research Technician
Kwasi Ofori, Research Assistant

General Research Interest

Development of immune-based methods for diagnosis, therapy, and prevention of infectious and toxin-mediated diseases of human, veterinary and/or zoonotic concern; animal model development; in vivo evaluation of candidate therapeutics; veterinary microbiology and parasitology.

Research and Clinical Interests

  • Passive Immunotherapy
  • Microbial Pathogenesis
  • Animal Model Development
  • Evaluation of Candidate Therapeutics
  • Conjugate Vaccines
  • One Health

 

 

Back to the Top

Selected Publications

  1. Mukherjee, J., C. McCann, K. Baldwin, K. Ofori, C. Taylor, J. Hill, C. Shoemaker, P. Harrison and S. Tzipori.  2012.  “Sheep Monoclonal Antibodies Prevent Systemic Effects of Botulinum Neurotoxin A1.”  Toxins  4(12):1565-1581.

  2. Mukherjee, J., J.M. Tremblay, C.E. Leysath, K. Ofori, K. Baldwin, X. Feng, D. Bedenice, S. Tzipori, and C.B. Shoemaker.  2011.  A Novel Strategy for Development or Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model.”  Plos One 7:1-7e29941.

  3. Sepulveda, J., J. Mukherjee, S. Tzipori, L. Simpson, C. Shoemaker.  2010.  “Efficient serum clearance of botulinum neurotoxin using a pool of small antitoxin binding agents."  Infection and Immunity  78(2):756-763.

  4. Mukherjee, J., K. Chios, D. Fishwild, D. Hudson, S. O’Donnell, S. Rich, A. Donohue-Rolfe, and S. Tzipori.  2002.  “Production and Characterization of Protective Human Antibodies Against Shiga-Toxin 1 (Stx1).”  Infection and Immunity 70(10):5896-5899.

  5. Mukherjee, J., K. Chios, D. Fishwild, D. Hudson, S. O’Donnell, S. Rich, A. Donohue-Rolfe, and S. Tzipori.  2002.  “Human Stx2 Antibodies Prevent Systemic Complications of Escherichia coli 0157:H7 Infection.”  Infection and Immunity  70(2):612-619.

  6. Mukherjee, J., M.D. Scharff, and A. Casadevall.  1995.  "Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Enhance Fluconazole Efficacy."  Antimicrobial Agents and Chemotherapy  39:1398-1405.

  7. Mukherjee, J., M.D. Scharff, and A. Casadevall.  1995.  "Variable Efficacy of Passive Antibody Administration Against Diverse Cryptococcus neoformans Strains."  Infection and Immunity  63:3353-3359.

  8. Mukherjee, J., G. Nussbaum, M.D. Scharff, and A. Casadevall.  1995.  "Somatic Mutation Can Generate Differences in Specificity that Change the Protective Efficacy of Antibodies to Cryptococcus neoformans."  Journal of Experimental Medicine  181:405-409.

  9. Mukherjee, J., L.S. Zuckier, M.D. Scharff, and A. Casadevall.  1994.  "Therapeutic Efficacy of Monoclonal Antibodies to Cryptococcus neoformans Glucuronoxylomannan Alone and in Combination with Amphotericin B."  Antimicrobial Agents and Chemotherapy  38:580-587.

  10. Mukherjee, J., L.-A. Pirofski, M.D. Scharff, and A. Casadevall.  1993.  "Antibody-Mediated Protection in Mice with Lethal Intracerebral Cryptococcus neoformans Infection."  Proceedings of the National Academy of Science (PNAS)  90:3636-3640.

  11. Mukherjee, J., A. Casadevall, and M.D. Scharff.  1993.  "Molecular Characterization of the Humoral  Responses to Cryptococcus neoformans Infection and Glucuronoxylomannan-Tetanus Toxoid Conjugate  Immunization."  Journal of Experimental Medicine  177:1105-1116.

 

Back to the Top