Education | Laboratory Personnel | General Research Interest | Selected Research Projects
Research and Clinical Interests | Major Specialized Equipment Items Available | Selected Publications

Melissa R. Mazan
Associate Professor
Director of Equine Sports Medicine Program
Department of Clinical Sciences
Sports Medicine
Phone: 508-839-5395 x84545
Fax: 508-839-7922
Email: melissa.mazan@tufts.edu

Education

DVM - Tufts University School of Veterinary Medicine - 1993
BA - Yale University - 1983

Teaching

  • Director of TCSVM/Massachusetts Equine Clinic Large Animal Medicine Internship
  • Equine sports medicine, equine exercise physiology, respiratory pathophysiology

Board Certification

  • American College of Veterinary Internal Medicine

General Research Interest

  • The equine respiratory system: Pathophysiology of small airway inflammatory disease - airway smooth muscle
  • Effects of particulate matter air pollution on equine respiratory disease
  • Resting energy in horses with recurrent airway obstruction
  • Non-invasive lung function testing
  • Stem cell applications in equine internal medicine
  • Role of the trophic macrophage in lung regeneration

Selected Publications

  1. Ingenito EP, Tsai L, Murthy S, Tyagi S, Mazan M, Hoffman A. Autologous lung-derived mesenchymal stem cell transplantation in experimental emphysema. Cell Transplant; Feb. 2011, epub ahead of print.
  2. Hoffman AM, Paxson JA, Mazan MR, Davis AM, Tyagi S, Murthy S, Ingenito EP. Lung derived mesenchymal stromal cell post-transplantaion survival, persistence, paracrine expression, and repair of elastase injured lung. Stem Cells Dev; 2011, epub ahead of print.
  3. Pacheco A, Bedenice D, Mazan M, Hoffman AM. Respiratory mechanics and bronchoalveolar lavage in healthy adult alpacas. Am J Vet Res 2011 (in press).
  4. Hoffman AM, Shifren A, Mazan MR, Gruntman AM, Lascola K, Nolen-Walston R, Kim CF, Tsai L, Pierce RA, Mecham R, and Ingenito EP. Matrix modulation of compensatory lung regrowth and progenitor cell proliferation in mice. Am J Physiol: Lung Cell Mol Physiol 2010; 298:L158-168. PMID 19915155.
  5. Paxson J, Parkin C, Iyer L, Mazan MR, Ingenito EP, and Hoffman AM. Global gene expression patterns during post-pneumonectomy lung regeneration in adult mice. Resp Res 2009; 10:92. PMID 19804646.
  6. Nolen-Walston RD, Kuehn H, Boston RC, Mazan MR, Wilkins PA, Bruns S, Hoffman AM. Reproducibility of airway responsiveness in horses using flowmetric plethysmography and histamine bronchoprovocation. J Vet Intern Med 2009; 23:631-635.
  7. Mazan MR, Merriam JG. Perspectives in Professional Education - A Description of the Tufts Cummings School of Veterinary Medicine - Massachusetts Equine Clinic Combined Equine Medicine Internship Program. JAVMA 2009, 235: 38-40.
  8. Mazan MR, Svatek J, Maranda L, Christiani D, Ghio A, Nadeau J, Hoffman AM. Questionnaire assessment of airway disease symptoms in equine barn personnel. Occup Med 2009; 59(4):220-225.
  9. Ceresia ML, Fasser CE, Rush JE, Scheife RT, Orcutt CJ, Michalski DL, Mazan MR, Dorsey MT, Bernardi SP. The role and education of the veterinary pharmacist. Am J Pharm Educ. 2009; 19:73:16.
  10. Nolen-Walston RD, Boston RC, Wilkins PA, Mazan MR, Kuehn H, Hoffman AM. Reproducibility of airway responsiveness using flowmetric plethysmography and histamine bronchoprovocation in horses. J Vet Int Med 2009; 23:631-635.