Hanping Feng
Associate Professor
Department of Biomedical Sciences
Infectious Diseases
Phone: 508-887-4252
Fax: 508-839-7911
Email: hanping.feng@tufts.edu
Feng Lab. URL: http://www.lablife.org/labs.2105
Dept. URL: http://www.tufts.edu/vet/biomed/infectious_diseases.htm
Education
PhD - University of Arizona - 2002
MS - Chinese Academy of Sciences - 1996
BS - University of Yangtz River - 1993
Laboratory Personnel
- Lianfa Shi: Research Associate
- Xingmin Sun: Research Associate
- Diane Schmidt: Postdoctoral Associate
- Gregorio Cordon: Postdoctoral Associate
- Kevin Chen: Research Assistant
- Weijia Nie: Research Assistant
- Yongrong Zhang: PhD student
- Haiying Wang: PhD student
General Research Interest
Host immune response to infectious agents; Signal transduction
Research Sponsor Interest
- Privately Funded Research
- Federally Funded Research
Selected Research Projects
- Clostridium difficile toxin-induced inflammatory response.
- Preventive and therapeutic measures against Clostridium difficile infection.
- Innate immune response and dendritic cells in Cryptosporidiosis.
Selected Publications
1. He X, Wang J, Steele J, Sun X, Nie W, Tzipori S, Feng H: An ultrasensitive rapid immunocytotoxicity assay for detecting Clostridium difficile toxins. J Microbiol Methods. 2009. 78(1):97-100.
2. Sun X, He X, Tzipori S, Gerhard R, Feng H: Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-alpha by macrophages. Microb Pathog. 2009. 46(6):298-305.
3. He X, Sun X, Wang J, Wang X, Zhang Q, Tzipori S, Feng H: Antibody-enhanced, Fc gamma receptor-mediated endocytosis of Clostridium difficile toxin A. Infect Immun. 2009. 77(6):2294-303.
4. Yang G, Zhou B, Wang J, He X, Sun X, Nie W, Tzipori S, Feng H: Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium. BMC Microbiol. 2008. 8:192.
5. Feng H, Nie W, Sheoran A, Zhang Q, Tzipori S: Bile acids enhance invasiveness of Cryptosporidium spp. into cultured cells. Infect Immun. 2006. 74(6):3342-6.
6. Feng H, Zhang D, Palliser D, Zhu P, Cai S, Schlesinger A, Maliszewski L, Lieberman J: Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation. J Immunol. 2005. 175(1):421-32.
7. Feng H, Zeng Y, Graner MW, Likhacheva A, Katsanis E. Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity. Blood. 2003. 101(1):245-52.