Education | Laboratory Personnel | General Research Interest | Selected Research Projects
Research and Clinical Interests | Major Specialized Equipment Items Available | Selected Publications
TCSVM Faculty

Sandra L. Ayres
Assistant Professor
Department of Biomedical Sciences
Section of Neuroscience and Reproductive Biology
Phone: 508-839-7956 ext. 84605
Fax: 508-839-7091
Email: sandra.ayres@tufts.edu

Education

DVM with Thesis - Tufts University - 1993
MA - Duke University - 1973
BS - Duke University - 1971

Board Certification

American College of Theriogenologists, 1999

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General Research Interest

Caprine Reproduction: Advanced reproductive techniques, particularly in relationship to transgenics and cloning.

Research Sponsor Interest:

  • Privately Funded Research
  • Federally Funded Research

Selected Research Projects:

  • Production of Cloned Goats
  • Superovulation in Goats without the Use of Exogenous Progesterone
  • Use of a Vital Fluorescent Stain to Detect Apoptosis in Oocytes and Embryos
  • Development of a Short Progesterone Protocol for Superovulation in Goats
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Major Specialized Equipment Items Available

  • Fluorescence microscope
  • Microinjection microscope
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Selected Publications

  1. Ebert, K. M., DiTullio, P., Barry, C.A., Schindler, J.E., Ayres, S.L., Smith, T.E., Pellerin, L.J., Meade, H.M., Denman, J., Roberts, B., Induction of human tissue plasminogen activator in the mammary gland of transgenic goats.  Bio/Tech., 12:699-702, 1994.

  2. Ayres, S.L., Wagner, P.,  Perirectal abscess in an American Miniature horse.  Equine Practice, 16(9):33-35, 1994.

  3. Baguisi A., Behboobi E., Melican D.T., Pollock J.S., Destrempes M.M., Williams, J.L., Nims, S.D., Porter C.A., Midura P., Palacios M.J., Ayres, S.L., Denniston R.S., Hayes M.L., Ziomek C.A., Meade H.M., Godke R.A., Gavin W.G., Overtröm E.W., Echelard Y.,  Production of goats by somatic cell nuclear transfer.  Nature Biotech., 15(5):456-461, 1999.

  4. Karuri, A.R., Ayres, S., Kumar, M.S.A., Regional distribution of gonadotropin-releasing hormone, beta-endorphin and met-enkephalin-like immunoreactivities in the central nervous system of the goat.  Brain Res. Bull., 51:63-68, 2000

  5. Singer, L.A., Kumar, M.S.A., Gavin, W., Ayres, S.L., Predicting the onset of parturition in the goat by determining progesterone levels by enzyme immunoassay.    Small Rum. Res. 52:203-209, 2004.

  6. Behboodi E.,  Ayres S.L., Memili E., O'coin M., Chen L.H., Reggio B.C., Landry A.M., Gavin W.G., Meade H.M., Godke R.A., Echelard Y.  Health and reproductive profiles of malaria antigen-producing transgenic goats derived by somatic cell nuclear transfer.  Cloning Stem Cells 7:107-118, 2005.

  7. Honaramooz, A., Behboodi, E., Hausler, C.L., Blash, S., Ayres, S., Azuma, C., Echelard, Y., Dobrinski, I.  Depletion of endogenous germ cells in male pigs and goats in preparation for germ cell transplantation.  J. Androl.  26: 698-705, 2005.

  8. Honaramooz, A., Megee, S., Zeng, W., Destrempes, M.M., Overton, S.A., Luo, J., Galantino-Homer, H., Modelski, M., Chen, F., Blash, S., Melican, D.T., Gavin, W.G., Ayres S., Yang,  F., Wang , P.J., Echelard, Y., Dobrinski, I.  Adeno-associated virus (AAV) -mediated transduction of male germ line stem cells results in transgene transmission after germ cell transplantation.  FASEB J. 22(2):374-82, 2008.

  9. Dorosko SM, Ayres SL, Connor RI.  Induction of HIV-1 MPR(649-684)-specific IgA and IgG antibodies in caprine colostrum using a peptide-based vaccine. Vaccine 26(42):5416-5422, 2008.

  10. Ayres, SL.  Early apoptosis in follicular versus ovulated oocytes in superovulated goats.   Clin Theriogenology  2(3):387, 2010.

     

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